Postmarketing conditions of respiratory despair, such as fatalities, have been noted with use of promethazine hydrochloride in pediatric individuals below two decades of age. A variety of excess weight-dependent doses of promethazine hydrochloride have resulted in respiratory depression in these patients.

This item could incorporate inactive elements, that may trigger allergic reactions or other problems. Discuss with your pharmacist for more particulars.

Codeine has become the Obviously happening phenanthrene alkaloids of opium derived from your nopium poppy; it is classified pharmacologically for a narcotic analgesic.

Serious hypotension commonly responds to the administration of norepinephrine or phenylephrine. EPINEPHRINE Shouldn't be Made use of, given that its use within a client with partial adrenergic blockade may perhaps further more reduce the blood pressure level.

Head Damage And Amplified Intracranial Force: The respiratory-depressant consequences of narcotic analgesics and their capacity to elevate cerebrospinal fluid force could be markedly exaggerated from the existence of head injuries, intracranial lesions or simply a preexisting rise in intracranial stress.

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This medication continues to be prescribed for the existing issue only. Don't utilize it afterwards for another situation unless advised to take action by your medical doctor. A different medication could be important in Individuals circumstances.

Treatment: The procedure of overdosage with promethazine and codeine is essentially symptomatic and supportive. Only in scenarios of maximum overdosage or specific sensitivity do essential indications including respiration, pulse, blood pressure level, temperature, and EKG must be monitored. Activated charcoal orally or by lavage may be offered, or sodium or magnesium sulfate orally to be a cathartic. Attention need to be supplied into the reestablishment of ample respiratory Trade by means of provision of the patent airway and institution of assisted or managed air flow.

Allergic reactions Convey to your medical professional For those who have at any time had any uncommon or allergic reaction to this medicine or some other medicines.

Codeine resembles morphine the two structurally and pharmacologically, but its steps within the Promethazine codeine syrup doses of codeine made use of therapeutically are milder, with less sedation, respiratory despair and gastrointestinal, urinary, and pupillary consequences. Codeine generates a rise in biliary tract stress, but under morphine or meperidine. Codeine is significantly less constipating than morphine.

This drug may well cause you to dizzy or drowsy or blur your eyesight. Alcoholic beverages or marijuana (cannabis) could make you a lot more dizzy or drowsy. Will not push, use machinery, or do anything that desires alertness or obvious vision until you are able to do it securely.

The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients below 6 a long time of age. Concomitant administration of promethazine products and solutions with other respiratory depressants has an Affiliation with respiratory depression, and from time to time Demise, in pediatric people. The association does in a roundabout way relate to individualized weight-dependent dosing, which could normally allow safe administration.

For the reason that narcotic analgesics may possibly increase biliary tract strain with resultant improves in plasma amylase or lipase stages, resolve of those enzyme ranges could be unreliable for 24 hrs following a narcotic analgesic has become supplied

Study the Medication Guide furnished by your pharmacist Before you begin taking promethazine/phenylephrine/codeine and every time you can get a refill. Should you have any concerns, ask your health practitioner or pharmacist.